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SHP099 Size:5mg Product Name DOTA-tris(t-Bu)ester-hexyne Synonyms CAS

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Description

Product Name DOTA-tris(t-Bu)ester-hexyne Synonyms CAS Number n/a Related CAS Molecular Formula C34H61N5O7 Molecular Weight 651

335 SMILES OCCCC#CC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

S)-AHPC-CO-C3-piperazine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C30H46Cl2N6O4S Molecular Weight 657

722 SMILES: [O-]C(=O)C1=CC(=CC=C1C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)C(=O)NCCCN=[N]#N Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

SHP099 Size:5mg Product Name DOTA-tris(t-Bu)ester-hexyne Synonyms CASSHP099 is a highly potent (IC50 = 0. 071uM),selective and orally bioavailable small molecule SHP2 inhibitor. The inhibiting SHP2 activity of SHP099 is through an allosteric mechanism. SHP099 suppresses RASERK signalling to inhibit the proliferation of receptor tyrosine kinase driven human cancer cells in vitro and is efficacious in mouse tumour xenograft models. Product Name SHP099 Synonyms CAS Number 1801747 42 1 Related CAS Molecular Formula

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